Tispa Medical’s proprietary histopathology process replaces toxic solvents like xylene with CO2. This is a reclaimed gas with unique features when pressure and temperature are adjusted to induce a supercritical phase.
A process time of only 3 hours for gross cut fatty tissues, like mammary and colon is achieved using a powerful mixture of supercritical CO2 and ethanol. No pre- or post-treatment of the tissues is required other than regular fixation. The processed tissues maintain cell morphology at new levels.
The timed release of ethanol into a retort, pressurized with CO2 enables the two to combine and dissolve into each other. Together they operate as a powerful solvent with low viscosity enabling a high diffusion rate and low surface tension. Once the ethanol and water are flushed out, paraffin is released in the retort to complete the process in minimal time.